Skip to main content
. 2020 Jun 14;12(6):1570. doi: 10.3390/cancers12061570

Figure 6.

Figure 6

Si306 and pro-Si306 inhibit the activity of Src downstream signaling pathway components in GBM cell lines. Representative Western blot images of pERK, extracellular signal-regulated kinase (ERK), pAKT and protein kinase B (AKT) protein expression in U87 and U87-TxR cells after 24 h treatment with 5 µM Si306 and pro-Si306 are shown. Histograms represent Western blot data expressed as phosphoprotein level relative to total protein level, normalized to β-tubulin. Values are expressed as mean ± SEM (n = 3). Statistical significance between treated and control group is shown as * (p < 0.05), ** (p < 0.01), and *** (p < 0.001), uncropped western blot in Figure S8.