Table 1.
DE cfmiRs in the plasma (P1 vs. P2) and serum (S1 vs. S2) samples of normal donors.
| (A) Top 10 DE cfmiRs expressed in duplicated plasma samples P1 and P2 | |||||
|---|---|---|---|---|---|
| Probe | Mean Normalized Expression P1 |
Mean Normalized Expression P2 |
FC P1 vs. P2 | p-Value | Adjusted p-Value |
| miR-6873-3p | 99 | 133 | 1.21 | 0.030 | 0.999 |
| miR-92b-3p | 269 | 369 | 1.17 | 0.081 | 0.999 |
| miR-1273e | 350 | 454 | 1.16 | 0.09 | 0.999 |
| miR-4274 | 120 | 109 | −1.09 | 0.138 | 0.999 |
| miR-1909-5p | 144 | 163 | 1.11 | 0.142 | 0.999 |
| miR-584-5p | 103 | 141 | 1.14 | 0.147 | 0.999 |
| miR-3157-5p | 101 | 115 | 1.1 | 0.179 | 0.999 |
| miR-6852-3p | 95 | 115 | 1.12 | 0.185 | 0.999 |
| miR-572 | 171 | 192 | 1.1 | 0.187 | 0.999 |
| miR-1287-5p | 371 | 430 | 1.11 | 0.190 | 0.999 |
| (B) Top 10 DE cfmiRs expressed in duplicated serum samples S1 and S2 | |||||
| Probe |
Mean Normalized
Expression S1 |
Mean Normalized
Expression S2 |
FC S1 vs. S2 | p-Value | Adjusted p-Value |
| miR-6819-5p | 149 | 103 | 1.36 | 0.0001 | 0.027 |
| miR-670-3p | 189 | 123 | 1.39 | 0.0001 | 0.030 |
| miR-1303 | 181 | 118 | 1.37 | 0.000 | 0.064 |
| miR-1273e | 2776 | 2058 | 1.26 | 0.009 | 0.418 |
| miR-193a-5p | 117 | 89 | 1.24 | 0.012 | 0.478 |
| miR-1290 | 229 | 160 | 1.26 | 0.017 | 0.555 |
| miR-1299 | 527 | 381 | 1.25 | 0.023 | 0.562 |
| miR-4769-3p | 120 | 102 | 1.15 | 0.027 | 0.588 |
| miR-6852-5p | 106 | 121 | −1.13 | 0.028 | 0.588 |
| miR-3674 | 473 | 357 | 1.21 | 0.048 | 0.703 |
DE = differentially expressed. CfmiRs = cell-free microRNAs. FC = fold-change. P1 = plasma 1. P2 = plasma 2. S1 = serum 1. S2 = serum 2. Highlighted in gray are the cfmiRs that were DE in serum samples.