Table 8.

29 DE cfmiRs in MBM patients’ plasma.

Probe	FC MBM-01 vs. Normal	Adjusted p-Value	FC MBM-02 vs. Normal	Adjusted p-Value
miR-3937	1.67	1.10 × 10−3	2.98	2.09 × 10−9
miR-1299	2.25	1.07 × 10−4	2.95	2.54 × 10−10
miR-1273e	3.36	2.30 × 10−10	2.79	1.13 × 10−12
miR-670-3p	1.78	3.53 × 10−5	2.66	2.96 × 10−24
miR-1225-3p	2.55	2.52 × 10−10	2.42	3.85 × 10−16
miR-574-5p	3.27	2.52 × 10−9	2.36	3.05 × 10−7
miR-6780b-5p	1.90	1.20 × 10−3	2.01	6.58 × 10−7
miR-3674	1.96	5.90 × 10−3	1.95	3.72 × 10−4
miR-7111-5p	1.69	6.50 × 10−3	1.89	1.30 × 10−6
miR-1273a	2.22	7.15 × 10−6	1.85	1.06 × 10−4
miR-6877-5p	1.53	2.92 × 10−2	1.84	2.85 × 10−5
miR-6775-5p	1.57	3.50 × 10−3	1.81	2.34 × 10−6
miR-4279	2.36	2.28 × 10−9	1.79	7.18 × 10−7
miR-5585-3p	1.77	5.80 × 10−3	1.69	3.48 × 10−4
miR-548d-5p	1.81	1.29 × 10−2	1.66	7.80 × 10−3
miR-7114-3p	1.88	1.70 × 10−6	1.65	2.27 × 10−8
miR-1207-5p	2.23	1.83 × 10−7	1.58	1.71 × 10−5
miR-3135a	2.12	1.08 × 10−5	1.55	6.26 × 10−4
miR-6789-3p	1.44	2.20 × 10−3	1.46	1.23 × 10−5
miR-1273c	1.67	6.20 × 10−3	1.41	1.63 × 10−2
miR-1228-3p	1.50	2.80 × 10−3	1.38	5.43 × 10−4
miR-1273g-5p	1.48	2.29 × 10−2	1.35	1.77 × 10−2
miR-143-5p	2.12	5.05 × 10−11	1.26	4.60 × 10−3
miR-6795-3p	−1.31	1.43 × 10−2	−1.26	7.06 × 10−4
miR-6126	–1.63	2.06 × 10−2	−1.36	1.90 × 10−2
miR-920	–1.64	1.51 × 10−8	−1.42	1.18 × 10−4
miR-378f	–2.02	4.64 × 10−10	−1.5	1.53 × 10−5
miR-3663-5p	–2.33	4.44 × 10−12	−1.7	2.23 × 10−5
miR-3184-3p	−1430.32	1.02 × 10−105	−2.07	2.78 × 10−11

DE = differentially expressed. CfmiRs = cell-free microRNAs. MBM-01 = melanoma brain metastasis first cohort. MBM-02 = melanoma brain metastasis second cohort. MBM = Melanoma brain metastasis. FC = fold-change.