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CKD-581 decreases anti-apoptotic proteins in DLBCL. (a) SU-DHL-4, (b) OCI-LY1, (c) SU-DHL-2, and (d) U2932 cells were treated with vehicle control (C), CKD-581 (10‒300 nM), or 300 nM SAHA (S) for 24 h, and total cell lysates were subjected to immunoblotting for BCL-xL and MCL-1. Data represent mean ± SEM (n = 3, significant vs. control; * p < 0.05, ** p < 0.01, *** p < 0.001).
