Table 3.

List of 30 somatic mutated genes significantly differentially expressed (DE), and also significantly differentially methylated (DM), between TNBC and non-TNBC.

Gene Symbol	Chromosome	DE p-Value	DM p-Value	DM Sites	TNBC Somatic Events	Non-TNBC Somatic Events
RBM22	5q33.1	2.21 × 10−10	5.04 × 10−10	7	3
CRIP1	14q32.33	2.75 × 10−22	4.17 × 10−27	17	2
CYP51A1	7q21.2	8.95 × 10−5	1.39 × 10−11	16	2
FAM227A	22q13.1	3.39 × 10−3	5.00 × 10−4	5	2
FHL3	1p34.3	3.32 × 10−5	1.11 × 10−15	9	2
GFI1	1p22.1	7.77 × 10−5	4.41 × 10−30	63	2
HCP5	6p21.33	2.04 × 10−3	6.76 × 10−10	39	2
HOXD13	2q31.1	6.69 × 10−7	5.98 × 10−21	9	2
IGSF21	1p36.13	2.82 × 10−7	6.04 × 10−28	50	2
P2RY2	11q13.4	3.33 × 10−12	1.59 × 10−19	15	2
PCBP3	21q22.3	1.64 × 10−8	9.13 × 10−24	42	2
RBM17	10p15.1	3.11 × 10−15	3.98 × 10−8	6	2
RNF26	11q23	1.99 × 10−3	1.28 × 10−4	4	2
SCAMP2	15q24.1	8.94 × 10−9	1.15 × 10−9	4	2
SCNN1B	16p12.2	3.39 × 10−2	4.08 × 10−17	9	2
MAP2K4	17p12	1.66 × 10−8	2.73 × 10−12	7		33
ZSWIM8	10q22.2	1.19 × 10−4	3.34 × 10−9	4		18
MALAT1	11q13.1	2.28 × 10−11	3.79 × 10−5	4		16
MED23	6q23.2	1.13 × 10−3	8.65 × 10−6	9		16
NRCAM	7q31.1	3.22 × 10−4	1.08 × 10−29	17		16
RAB3GAP2	1q41	3.04 × 10−3	9.49 × 10−15	8		16
KIAA0100	17q11.2	1.13 × 10−6	3.46 × 10−7	5		15
ABCC4	13q32.1	8.68 × 10−8	1.04 × 10−18	17		13
MED13L	12q24.21	1.46 × 10−13	7.41 × 10−23	12		13
RIPK1	6p25.2	1.87 × 10−6	3.25 × 10−14	10		13
TIAM2	6q25.2-q25.3	1.83 × 10−4	1.67 × 10−23	36		13
ADAMTS16	5p15.32	2.51 × 10−4	6.92 × 10−17	32		12
ADGB	6q24.3	5.90 × 10−12	1.05 × 10−3	5		12
PHF8	Xp11.22	7.01 × 10−7	4.42 × 10−8	6		12
RGS7	1q43	1.30 × 10−4	2.95 × 10−18	26		12