Table 2.
Formulation (BP%) | Z-Average (nm) | PDI | %EE (±SD) |
---|---|---|---|
LipoD (0%) | 211.2 ± 0.60 | 0.08 ± 0.03 | 0 |
CDD3 (18%) | 253.0 ± 6.05 | 0.33 ± 0.01 | 58.2 ± 2.3 |
CDD2 (22%) | 331.4 ± 4.74 | 0.47 ± 0.06 | 89.9 ± 1.0 |
CDD1 (25%) | 360.9 ± 23.06 | 0.53 ± 0.07 | 98.4 ± 3.7 |
Abbreviation: PDI: polydispersity index; BP%: initiative weight percentage of BP; %EE: encapsulation efficiency (%); LipoD: comprising DMPC and cholesterol; CDD: BP represents the (2-hydroxypropyl)-β-cyclodextrin (CD)/LipoD formulation.