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The generation of hepcidin in the inflammatory process. STAT3 activation requires the presence of SAMD4 because its absence prevents STAT3-mediated hepcidin gene expression [58]. This process can be framed within the inflammatory process of AP. IL: interleukin; STAT3: signal transducer and activator of transcription-3; HAMP: hepcidin antimicrobial peptide.
