Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 26;12(6):1350. doi: 10.3390/cancers12061350

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Proteins. Heatmap (A) and volcano plot (B), visualizing abundance distributions and significant differences of proteins, respectively, in cerebrospinal fluid (CSF) of medulloblastoma (MB) and reference (Ref) samples. Difference values in the volcano plot are shown in a logarithmic scale to the basis of 2. Proteins were additionally classified according to the gene ontology term “leukocyte mediated immunity [2443]” and/or “defense response [6952]” (LMI-DR), and according to existing literature into anti-inflammatory proteins (AI), proteins related to brain function (BF), hypoxia-related proteins (HYP), pro-inflammatory proteins (PI), tumor markers (TM) and tumor promotors (TP). Principal component analysis (C) demonstrates the group separation of neoplastic medulloblastoma (MB) and non-neoplastic reference (Ref) samples based on investigated proteins.