AKAP12 |
A-kinase anchor protein 12 |
AKT |
Protein kinase B |
APOBEC |
Apolipoprotein B mRNA Editing Catalytic Polypeptide-like |
ARID1A |
AT-Rich Interaction Domain 1A |
ATM |
ATM serine/threonine kinase |
ATR |
ATR serine/threonine kinase |
AURKA |
Aurora kinase A |
BARD1 |
BRCA1 associated RING domain 1 |
BAX |
BCL2 associated X, apoptosis regulator |
BCL2 |
BCL2 apoptosis regulator |
BCL2L1 |
BCL2 like 1 |
BENE |
Benzoate transport protein |
Bit1 |
Bcl2-inhibitor of transcription 1 |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
BRCA1 |
BReast CAncer gene 1 |
BRCA2 |
BReast CAncer gene 2 |
BRIP1 |
BRCA1 interacting protein C-terminal helicase 1 |
CASP4 |
Caspase 4 |
CCNA2 |
Cyclin-A2 |
CCNB1 |
Cyclin-B1 |
CCND1 |
Cyclin-D1 |
CCNE1 |
Cyclin-E1 |
CCOC |
Clear cell ovarian cancer |
CDC25 |
Cell division cycle 25 homolog A |
CDH6 |
Cadherin-6 |
CDK |
Cyclin-dependent kinases |
CDK1 |
Cyclin-dependent kinases 1 |
CDK12 |
Cyclin-dependent kinases 12 |
CDK2 |
Cyclin-dependent kinases 2 |
CDKN2A |
Cyclin-dependent kinase inhibitor 2A |
CHEK1 |
Checkpoint kinase 1 |
CHEK2 |
Checkpoint kinase 2 |
COPI |
COPI-coated vesicles |
CREBBP |
CREB-binding protein |
CSE1L |
Human homolog of the yeast cse1gene |
CSMD3 |
CUB and Sushi multiple domains 3 |
CTNNB1 |
Catenin beta 1 |
CTSD |
Cathepsin D |
CXCL11 |
C-X-C motif chemokine 11 |
CXCR7 |
C-X-C Chemokine Receptor Type 7 |
CYR61 |
Cysteine rich angiogenic inducer 61 |
DDR |
DNA damage response |
DES |
Desmin |
DOT1L |
Disruptor of telomeric silencing-1-like |
DSB |
Double-strand DNA breaks |
DYNLL1 |
Dynein light chain LC8-type 1 |
E2 |
17β-estradiol |
EIF2 |
Eukaryotic translation initiation factor 2 |
EIF2B1 |
Eukaryotic translation initiation factor 2B subunit alpha |
EIF2B2 |
Eukaryotic translation initiation factor 2B subunit beta |
EIF2B3 |
Eukaryotic translation initiation factor 2B subunit gamma |
EIF2B4 |
Eukaryotic translation initiation factor 2B subunit delta |
EIF2B5 |
Eukaryotic translation initiation factor 2B subunit epsilon |
EIF4E |
Eukaryotic translation initiation factor 4E |
EOC |
Epithelial ovaria cancer |
EOVC |
Endometrioid ovarian cancers |
ERBB2 |
Erb-b2 receptor tyrosine kinase 2 |
ERCC |
NA excision repair protein ERCC-1-like protein |
ERCC2 |
ERCC excision repair 2 |
ERCC3 |
ERCC excision repair 3 |
ERE |
Estrogen-response element |
ERK |
Extracellular regulated MAP kinase |
ERα |
Estrogen receptor α |
ERβ |
Estrogen receptor β |
ESR1 |
Estrogen receptor 1 |
ESR2 |
Estrogen receptor 2 |
FAT3 |
FAT atypical cadherin 3 |
FOSL1 |
FOS like 1, AP-1 transcription factor subunit |
FOXM1 |
Forkhead box M1 |
FPP |
Farnesyl pyrophosphate |
GABRA6 |
Gamma-aminobutyric acid type A receptor subunit alpha6 |
GGPP |
Geranylgeranyl pyrophosphate |
GO |
Gene Ontology |
GRSF1 |
G-rich RNA sequence binding factor 1 |
HDAC3 |
Histone deacetylase 3 |
HDI |
Human Development Index |
HER2 |
Human epidermal growth factor receptor 2 |
HGSOC |
High-grade serous ovarian cancer |
HMG-CoA |
Hydroxymethyl-glutaryl coenzyme A |
HMGCR |
Hydroxymethyl-glutaryl reductase |
HR |
Homologous recombination |
HRT |
Hormone replacement therapy |
hTER |
Telomerase reverse transcriptase |
HUS1 |
HUS1 checkpoint clamp component |
ID4 |
Inhibitor of DNA binding 4, HLH protein |
IGFBP3 |
Insulin like growth factor binding protein 3 |
IPA |
Ingenuity Pathway Analysis |
IRF2BP2 |
Interferon regulatory factor 2 binding protein 2 |
KMT2B |
Lysine methyltransferase 2B |
KMT2D |
lysine methyltransferase 2D |
KPNB1 |
Karyopherin subunit beta 1 |
KRAS |
KRAS proto-oncogene, GTPase |
KRT |
Keratin |
LCN2 |
Lipocalin-2 |
LGSOC |
Low-grade serous ovarian cancer |
LOH |
Loss of heterozygosity |
MAPK |
Mitogen-Activated Protein Kinase |
MECOM |
MDS1 and EVI1 complex locus |
MED |
Mediator Complex |
MED14 |
Mediator Complex Subunit 14 |
MED17 |
Mediator Complex Subunit 17 |
MED18 |
Mediator Complex Subunit 18 |
MED20 |
Mediator Complex Subunit 20 |
MED21 |
Mediator Complex Subunit 21 |
MED30 |
Mediator Complex Subunit 30 |
MED4 |
Mediator Complex Subunit 4 |
MED6 |
Mediator Complex Subunit 6 |
MLH1 |
MutL homolog 1 |
MMP |
Matrix metalloproteinase |
MMR |
DNA mismatch repair |
MOC |
Mucinous ovarian cancers |
Mre11 |
MRE11 homolog, double strand break repair nuclease |
MTOR |
Mammalian target of rapamycin |
MTORC1 |
Mammalian target of rapamycin complex 1 |
MUTYH |
MutY DNA glycosylase |
MYC |
MYC proto-oncogene |
NBS1 |
Nijmegen Breakage Syndrome 1 |
NER |
Nucleotide excision repair |
NF1 |
Neurofibromin 1 |
NOTCH4 |
Notch Receptor 4 |
NRAS |
NRAS proto-oncogene, GTPase |
OC |
Ovarian cancer |
P16 |
Cyclin-dependent kinase inhibitor 2A |
P21 |
Cyclin-dependent kinase inhibitor 1 |
P27 |
Cyclin-dependent kinase inhibitor 1B |
PALB2 |
Partner and localizer of BRCA2 |
PARP |
Poly ADP ribose polymerase |
PAX2 |
Paired box gene 2 |
PAX8 |
Paired box gene 8 |
PCNA |
Proliferating cell nuclear antigen |
PERK |
Protein kinase-like Endoplasmic Reticulum Kinase |
PGR |
Progesterone receptor |
PIK3C3 |
Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3 |
PI3K |
Phosphatidylinositol 3-kinase |
PI3KCA |
Phosphatidylinositol 3-kinase catalytic alpha polypeptide |
PLAU |
Plasminogen activator, urokinase |
PLC |
Phospholipase C |
PLK1 |
Polo like kinase 1 |
POLE |
DNA polymerase epsilon, catalytic subunit |
POT1 |
Protection of telomeres 1 |
PP2R1A |
Protein phosphatase 2, regulatory subunit A |
PPP1CB |
Protein Phosphatase 1 Catalytic Subunit Beta |
PPP1R12A |
Protein Phosphatase 1 Regulatory Subunit 12A |
PPP2R1A |
Protein Phosphatase 2 Scaffold Subunit Aalpha |
PTEN |
Phosphatase and tensin homolog |
Rab |
Rab Family Small GTPase |
Rac |
Rac Family Small GTPase |
RAD1 |
RAD1 checkpoint DNA exonuclease |
RAD50 |
RAD50 double strand break repair protein |
RAD51 |
RAD51 recombinase |
RAD51C |
RAD51 paralog C |
RAD51D |
RAD51 paralog D |
RAD9 |
Checkpoint Clamp Component A |
RAN |
Ras-related nuclear protein |
RAP1 |
Ras-related protein 1 |
RASSF1gene |
Ras Association Domain Family Member 1 |
RB1 |
Retinoblastoma protein |
RCF3 |
Replication factor C subunit 3 |
RFC |
Replication factor C |
Rho |
Rhodopsin |
RhoA |
Ras homolog family member A |
RPA |
Replication Protein A |
RPA3 |
Replication Protein A3 |
RRAS2 |
Ras-Related Protein R-Ras2 |
STK11 |
Serine/threonine kinase 11 |
TCGA |
The Cancer Genome Atlas |
TERF1 |
Telomeric Repeat Binding Factor 1 |
TERF2 |
Telomeric Repeat Binding Factor 2 |
TFAP4 |
Transcription Factor AP-4 |
TGFBI |
Transforming Growth Factor Beta Induced |
TIGAR |
TP53 induced glycolysis and apoptosis regulator |
TINF2 |
TERF1 Interacting Nuclear Factor 2 |
TNFSF7 |
Tumor Necrosis Factor Ligand Superfamily Member 7 |
TP53 |
Tumor protein p53 |
TPP1 |
Tripeptidyl peptidase 1 |
TRAM1 |
Translocation associated membrane protein 1 |
TRAP1 |
TNF receptor associated protein 1 |
UBL1 |
Ubiquitin-like protein 1 |
UPR |
Unfolded protein response |
VEGF |
Vascular endothelial growth factor |
VIM |
Vimentin |
WEE1 |
WEE1 G2 checkpoint kinase |
ZMYND8 |
Zinc finger MYND-type containing 8 |
ZNF587B |
Zinc finger protein 587B |