Figure 2.

Pivotal role of glutamine stored in muscle (glutamine “bank”), normal high glutamine concentration in plasma, and liver amino acid metabolism (switch hitter) to facilitate steady state glutamine for mucosal health in (A) healthy anabolic state versus (B) during catabolic states including injury from cancer therapy, malnutrition, and tissue damage. In the catabolic state of mucositis from cancer therapy injury, topical glutamine + disaccharide can be helpful.