Table 2.
Baseline general characteristics of the subjects.
| PTE Group | Placebo Group | Total | p-Value 1 | |
|---|---|---|---|---|
| (n = 58) | (n = 53) | (n = 111) | ||
| Sex (M/F) (n.%) | 9(15.5)/49(84.5) | 10(18.9)/43(81.1) | 19(17.1)/92(82.9) | 0.640 2 |
| Age (years) | 59.6 ± 4.8 | 59.9 ± 6.1 | 59.8 ± 5.5 | 0.718 |
| Height (cm) | 158.3 ± 6.5 | 157.9 ± 7.5 | 158.1 ± 7.0 | 0.803 |
| Weight (kg) | 60.1 ± 8.1 | 59.3 ± 10.1 | 59.7 ± 9.1 | 0.651 |
| BMI (kg/m2) | 23.9 ± 2.7 | 23.7 ± 3.1 | 23.8 ± 2.8 | 0.615 |
| SBP (mmHg) | 120.7 ± 15.6 | 120.1 ± 17.7 | 120.4 ± 16.6 | 0.852 |
| DBP (mmHg) | 70.4 ± 10.8 | 69.7 ± 11.9 | 70.1 ± 11.3 | 0.740 |
| Pulse (bpm) | 69.3 ± 9.6 | 69.6 ± 9.2 | 69.5 ± 9.4 | 0.869 |
| NK cell activity 12.5:1 (%) |
11.4 ± 8.4 | 11.8 ± 9.1 | 11.6 ± 8.7 | 0.828 |
| 25:1 (%) | 20.6 ± 12.2 | 20.7 ± 13.6 | 20.6 ± 12.8 | 0.992 |
| 50:1 (%) | 28.0 ± 14.3 | 27.4 ± 14.3 | 27.7 ± 14.3 | 0.837 |
| IL-2 (pg/mL) | 1.28 ± 0.85 | 1.44 ± 1.51 | 1.36 ± 1.21 | 0.462 |
| IL-6 (pg/mL) | 0.64 ± 0.69 | 0.63 ± 0.85 | 0.63 ± 0.77 | 0.982 |
| IL-12 (pg/mL) | 2.31 ± 1.86 | 2.08 ± 1.49 | 2.20 ± 1.69 | 0.466 |
| INF-γ (pg/mL) | 8.35 ± 8.68 | 7.04 ± 6.97 | 7.72 ± 7.90 | 0.384 |
| TNF-α (pg/mL) | 6.05 ± 2.47 | 7.36 ± 2.82 | 6.68 ± 2.71 | 0.011 |
| Alcohol (n, %) | 23(39.7)/35(60.3) | 27(50.9)/26(49.1) | 50(45.1)/61(55.0) | 0.233 2 |
| Alcohol (unit 3/week) | 1.54 ± 2.24 | 3.30 ± 4.51 | 2.49 ± 3.72 | 0.082 |
| Smoking (Y/N) | 0(0.0)/58(100.0) | 2(3.8)/51(96.2) | 2(1.8)/109(98.2) | 0.226 4 |
| Smoking (cigarettes/day) | 0.00 ± 0.00 | 12.5 ± 3.5 | 12.5 ± 3.5 | - |
Values are presented as mean ± standard deviation (SD) or number. 1 Analyzed using independent t-test. 2 Analyzed using chi-square test. 3 Alcohol 1 unit = Alcohol 10 g = Alcohol 12.5 mL. 4 Analyzed using Fisher’s exact test. Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; NK, natural killer; interleukin-2, 6, 12 (IL-2, IL-6, IL-12); INF-γ, interferon gamma; TNF-α, tumor necrosis factor alpha.