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. 2020 Jun 9;12(6):1500. doi: 10.3390/cancers12061500

Table 2.

Synthetic PAH is as effective as natural PAH to increase dxr cytotoxicity against melanoma cells. IC50 values were calculated using GraphPad Prism 6 software. Mean ± SEM of 3 independent experiments are presented.

Heading Treatment IC50 (µM)
With Natural PAH With Synthetic PAH
MeWo cells Dxr (at 20 µM PAH) 0.5 ± 0.1 1.1 ± 0.4
PAH at 2 µM Dxr 6.6 ± 0.8 8.1 ± 1.3
A375 cells Dxr (at 20 µM PAH) 0.5 ± 0.1 0.6 ± 0.2
PAH at 2 µM Dxr 12.4 ± 4.9 12.4 ± 2.3