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Seven Strains with Discordant Phenotype to Genotype Resistance to CLA and LEV
| Strain Number | MIC (μg/mL) | Mutations of 23S rRNA | Mutations of gyrA | |
|---|---|---|---|---|
| CLA | LEV | |||
| 1 | 4 | 0.25 | – | – |
| 18 | 0.03 | 2 | – | – |
| 21 | 0.06 | 4 | – | – |
| 23 | 2 | 0.06 | – | – |
| 47 | 8 | 0.25 | – | – |
| 22 | 0.06 | 0.25 | A2143G | – |
| 37 | <0.0156 | 16 | A2143G | N87K |
Notes: CLA > 0.5 μg/mL is sensitive, LEV > 1 μg/mL is sensitive.
Abbreviations: A, adenine; CLA, clarithromycin; G, guanine; LEV, levofloxacin; MIC, minimal inhibitory concentration; -, no mutation.
