ADAM	a disintegrin and metalloproteinases
AF1	activation function 1
AF2	activation function 2
Akt	protein kinase B
Ang II	angiotensin II
ApoE	apolipoprotein E-deficient
BMPR2	bone morphogenetic protein receptor type 2
BP	blood pressure
c-SRC	proto-oncogene tyrosine-protein kinase
CVD	cardiovascular disease
EF	ejection fraction
EGFR	epidermal growth factor receptor
ERK1/2	extracellular signal-regulated protein kinases 1 and 2
eNOS	endothelial nitric oxide synthase
ER	estrogen receptor
ERα	estrogen receptor alpha
ERβ	estrogen receptor beta
ERE	estrogen response element
ERK	extracellular-signal-regulated kinase
E2	17beta-estradiol
GPER	G protein–coupled estrogen receptor 1
GPR30	G-protein-coupled estrogen receptor
GSK-3β	glycogen synthase kinase 3
HF	heart failure
HFrEF	heart failure with reduced ejection fraction
HFpEF	heart failure with preserved ejection Fraction
HIF-1α	hypoxia-inducible factor 1α
HTN	hypertension
iNOS	inducible nitric oxide synthase
I/R injury	ischemia-reperfusion injury
JNK	c-Jun N-terminal kinase
KO	knockout
LDL	low-density lipoprotein
LV	left ventricular
LVEF	left ventricular ejection fraction
MAPK	mitogen-activated protein kinase
MCT	monocrotaline
NO	nitric oxide
NOS	nitric oxide synthase
NOX4	NAD(P)H oxidase
OVX	ovariectomized
PAH	pulmonary arterial hypertension
PASMC	pulmonary artery smooth muscle cell
PH	pulmonary hypertension
PI3K	phosphoinositide-3-kinase
P53	tumor protein p53
RV	right ventricular
RVEF	right ventricular ejection fraction
RAS	renin-angiotensin system
ROS	reactive oxygen species
SERT	serotonin transporter
Su/Hx PH	SU5416/hypoxia-induced pulmonary hypertension
TAC	transverse aortic constriction
TGF	transforming growth factor
VSMC	vascular smooth muscle cells
WT	wildtype