CTCs |
Circulating Tumor Cells |
WGA |
Whole Genome Amplification |
NGS |
Next-Generation Sequencing |
ctDNA |
Circulating tumor DNA |
BC |
Breast Cancer |
MDA |
MDA-MB-231 |
EpCAM |
Epithelial Cell Adhesion Molecule |
FITC |
fluorescein isothiocyanate |
PE |
phycoerythrin |
APC |
allophycocyanin |
FACS |
Fluorescent-Activated Cell Sorter |
PCR |
Polymerase Chain Reaction |
OBcfRAv2 |
Oncomine Breast cfDNA Research Assay v2 |
KRAS |
Kirsten rat sarcoma 2 viral oncogene homolog |
TP53 |
Tumor Protein 53 |
MAFs |
Molecular Allele Frequencies |
VFSH |
Variant Family Size Histogram |
TVC |
Torrent Variant Caller |
PIK3CA |
Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha |
ERBB2 |
Erb-B2 Receptor Tyrosine Kinase 2 |
ERBB3 |
Erb-B2 Receptor Tyrosine Kinase 3 |
ERBB4 |
Erb-B2 Receptor Tyrosine Kinase 4 |
ESR1 |
Estrogen Receptor 1 |
MCL1 |
MCL1 Apoptosis Regulator |
GATA3 |
GATA Binding Protein 3 |
PTEN |
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase |
CCND1 |
Cyclin D1 |
AKT1 |
v-akt murine thymoma viral oncogene homolog 1 |
CDH1 |
Cadherin 1 |
MAP2K4 |
Mitogen-Activated Protein Kinase Kinase 4 |
SF3B1 |
Splicing factor 3b subunit 1 |
FBXW7 |
F-box/WD repeat-containing protein 7 |
MAP3K1 |
Mitogen-Activated Protein Kinase Kinase Kinase 1 |
PIK3R1 |
Phosphoinositide-3-Kinase Regulatory Subunit 1 |
EGFR |
Epidermal Growth Factor Receptor |
FGFR1 |
Fibroblast Growth Factor Receptor 1 |
FFPE |
Formalin-Fixed Paraffin-Embedded |
BAM |
Binary Alignment Map |
VCF |
Variant Caller Format |
IGV |
Integrative Genomic Viewer |
TMAP |
Torrent Mapping Alignment Program |
DMEM |
Dulbecco’s Modified Eagle Medium |
PBS |
Phosphate Buffered Saline |
BEAMing |
Beads, Emulsions, Amplification, and Magnetics |