Table A1.

Imaging techniques for NSCLC diagnosis.

Positron Emission Tomography (PET). Detects pairs of gamma rays emitted by a radioligand previously introduced in the body after the combination of the introduced positrons with electrons from the patients’ body. Thus, it requires the use of contrast agents conjugated to a biologically relevant molecule, involved in the disease to be detected [15,35,152]. Computed Tomography (CT). Measures the attenuation of X rays emitted after interacting with tissues. It may require contrast agents if the difference of attenuation after interaction with different tissues of interest is not evident. After the acquisition, cross-sectional images are obtained using tomographic reconstruction [15,35,152]. Magnetic Resonance Imaging (MRI). Measures changes in the nuclear momentum of atoms while applying an external magnetic field. Hydrogen atoms are usually evaluated due to their simplicity and abundance in the human body. The relaxing times of H atoms in different tissues are measured to obtain images [15,35,152]. Does not require contrast agents. Bronchoscopy. Imaging technique consisting of the use of flexible bronchoscopy, including a camera, to visualize the inside of the airways for diagnostic and therapeutic purposes [22,35,153]. Mediastinoscopy. Small incision in the center of the thoracic cavity to section a small part of the tissue for biopsy purposes [22,35,153]. Bronchoalveolar lavage (BAL). Introduction of a measured volume of fluid in the lungs through the appropriate airways for further examination [22,35,153].