Table 3.
Molecular data of breast cancer cell lines in comparison to normal breast cell lines.
Receptor Status | Subtype | ||||
---|---|---|---|---|---|
Cell Lines | Estrogen Receptor (ER) | Progesterone Receptor (PR) | Human Epithelial Receptor (HER2) | Histologic | Molecular |
MCF-7 | + | + | - | invasive ductal carcinoma | Luminal A |
MDA-MB-231 | - | - | - | adenocarcinoma | Triple negative B |
MDA-MB-468 | - | - | - | adenocarcinoma | Triple negative A |
BT549 | - | - | - | invasive ductal carcinoma | Triple negative B |
SUM149 | - | - | - | inflammatory ductal carcinoma | Triple negative B |
SUM159 | - | - | - | anaplastic carcinoma | Triple negative B |
BT-20 | - | - | - | invasive ductal carcinoma | Triple negative A |
SK-BR-3 | - | - | + | adenocarcinoma | HER2 positive |
T47D | + | + | - | invasive ductal carcinoma | Luminal A |
ZR-75-1 | + | - | - | invasive ductal carcinoma | Luminal A |
MCF-12A | - | - | - | non-tumorigenic fibrocystic breast epithelium | basal |
MCF-10A/F | - | - | - | non-tumorigenic fibrocystic breast epithelium | basal |