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. 2020 Jun 13;21(12):4225. doi: 10.3390/ijms21124225

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cell-permeable NBD peptide decreased podocyte loss and basement membrane thickness in BTBR ob/ob mouse kidney. (A) Representative images of WT-1 immunohistochemistry (magnification 630×) and quantification of WT-1⁺ cells in glomerular cross section (gcs). Transmission electron microscopy images (magnification 9900×) and measurement of (B) glomerular basement membrane (GBM) and (C) tubular basement membrane (TBM) thickness. Data shown as scatter dot plots and mean ± SD of each group (n = 6–8 mice/group). *** p < 0.001; **** p < 0.0001 vs. diabetic vehicle control.