Figure 3.

Sphere formation efficiency of ovarian cancer cells exposed to the drugs. (A) The drugs break apart pre-formed spheroids after exposure to drugs for 72 h in OV90 cell line (top) and OVCAR8 (bottom). (B) OV90 sphere formation efficiency was quantified in increasing concentrations of drugs as number of spheroids over 1000 µm². Graphs represent mean and SEM Graphs represent mean and SEM of each treatment, distinguished by different degrees of grayscale shading * p < 0.05, ** p < 0.01, *** p < 0.001 compared to vehicle control.