Table 1.
Dose–volume histogram metrics for different tissue structures (tumor, right brain (R brain) without tumor, and left brain (L brain)) in treated animals (20, 30 or 60 Gy as indicated) using the AP-PA radiation treatment plan (Plan 4). Numbers are the mean and standard deviation of n ≥ 7 animals per treatment group. D95 = dose to 95% of the target volume; D5 = dose to 5% of the target volume.
| Planned Dose (Gy) | Tumor Dose (Gy) | R Brain without Tumor Dose (Gy) | L Brain | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | D95 | D5 | Mean | D95 | D5 | Mean | D95 | D5 | |
| 20 Gy | 19.4 ± 0.3 | 16.8 ± 0.2 | 22.2 ± 0.3 | 3.8 ± 0.3 | 0.00 | 20.0 ± 0.4 | 0.11 ± 0.1 | 0.00 | 0.09 ± 0.1 |
| 30 Gy | 28.1 ± 3.0 | 21.3 ± 11 | 30.4 ± 0.3 | 4.1 ± 1.5 | 0.08 ± 0.0 | 26.1 ± 7.6 | 0.58 ± 0.4 | 0.07 ± 0.1 | 1.1 ± 1.0 |
| 60 Gy | 59.2 ± 1.5 | 54.1 ± 9.4 | 61.0 ± 0.4 | 9.3 ± 3.8 | 0.22 ± 0.1 | 52.9 ± 19 | 1.2 ± 0.9 | 0.19 ± 0.1 | 3.0 ± 4 |