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. 2020 Jun 11;12(6):1541. doi: 10.3390/cancers12061541

Figure 2.

Figure 2

RAC1-mediated signaling in tumorigenesis: the cartoon presents the cellular signaling involving the activation of RAC1 in solid tumors. Following the activation of RAC1, a number of oncogenic cellular pathways are activated in tumor cells. The specific modes of involvement of the pathways and phenotypes are presented in the context of different mechanisms of activation(s) of RAC1 in different organ-type cancer(s).