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. 2020 Jun 11;12(6):1535. doi: 10.3390/cancers12061535

Table 3.

Lack of prognostic value of immune signature expression in LUSC patients.

Immune Signatures Overall Female Male
IFN-G - - -
Lymphocytes infiltration - - -
Macrophage-Monocytes - - -
TGF-β - - -
Wound healing - - -

Note for Table 2: For Overall, Female, and Male cohorts, respectively, the median expression value for each gene signature was calculated and compared to each individual patient gene signature mean expression, to classify patients into either the ‘High’ or ‘Low’ cohorts, respectively. The p-value for the log-rank test of differences in overall survival time between ‘High’ and ‘Low’ expression cohorts was calculated. Considering the relative survival between the ‘High’ and ‘Low’ cohorts respectively, if the p-value < 0.05, the gene signature was categorized as having either an “Extended” (blue) or “Poorer” (red) prognostic impact on survival. Otherwise, the gene signature was labeled ‘-’, as having no significant prognostic impact on survival.