Table 1.
Association of telomere length and clinicopathological factors in patients with ovarian, cervical, and endometrial cancer.
| Ovarian Cancer | ||||
| Factors | No. of cases (N) | Long RLT | Short RLT | p -Value |
| Age (years) | 60.15(14.11) | 69.53(10.71) | 0.002 a | |
| Grade | ||||
| G1 | 15 | 9(60%) | 6(40%) | 0.69 b |
| G2, G3 | 57 | 31(54.38%) | 26(45.61%) | |
| FIGO stage | ||||
| I, II | 44 | 29(65.90%) | 15(34.09%) | 0.027 b |
| III, IV | 28 | 11(39.28%) | 17(60.71%) | |
| Histology | ||||
| Serous | 35 | 17(48.57%) | 18(51.42%) | 0.49 b |
| others | 37 | 15(40.54%) | 22(59.45%) | |
| Residual Tumor | ||||
| <1cm | 54 | 34(62.96%) | 20(37.03%) | 0.028 b |
| ≥1cm | 18 | 6(33.33%) | 12(66.66%) | |
| Cervical Cancer | ||||
| Factors | No. of cases | Long RLT | Short RLT | p -Value |
| Age (years) | 48.73(13.93) | 58.35(13.57) | 0.033 a | |
| FIGO Stage | ||||
| I & IIa | 45 | 30(66.66%) | 15(33.33%) | 0.001 b |
| IIb, III, IV | 18 | 4(22.22%) | 14(77.77%) | |
| Histology | ||||
| SCC | 33 | 16(48.48%) | 17(51.51%) | 0.36 b |
| AC/ASC | 30 | 12(40%) | 18(60%) | |
| Endometrial Cancer | ||||
| Factors | No. of cases | Long RLT | Short RLT | p -Value |
| Age (years) | 61.19(13.08) | 59.17(12.85) | 0.021 a | |
| Grade | ||||
| GI | 47 | 28(59.57%) | 19(40.42%) | 0.17b |
| G2, G3 | 40 | 18(45.00%) | 22(55.00%) | |
| FIGO Stage | ||||
| I, II | 67 | 41(61.19%) | 26(38.80%) | 0.004b |
| III, IV | 20 | 5(25%) | 15(75%) | |
| Histology | ||||
| Endometroid | 72 | 34(47.22%) | 38(52.77%) | 0.96b |
| Others | 15 | 7(46.66%) | 8(66.66%) | |
| Lymph node metastasis | ||||
| Negative | 78 | 45(57.69%) | 33(42.30%) | 0.008b |
| Positive | 9 | 1(11.11%) | 8(88.88%) | |
| Lymph vascular space | ||||
| Negative | 48 | 31(64.58%) | 17(35.41%) | 0.015b |
| Positive | 39 | 15(38.46%) | 24(61.53%) | |
| Myometrial invasion | ||||
| a, b | 65 | 30(46.15%) | 35(53.84%) | 0.75b |
| c | 22 | 11(50%) | 11(50%) | |
| Menopause | ||||
| Pre | 30 | 16(53.33%) | 14(46.66%) | 0.40b |
| Post | 57 | 32(56.14%) | 25(43.85%) | |
Notes: FIGO, International Freedom of Gynecology and Obstetrics; RLT, relative lymphocyte telomere length; SCC, squamous cell carcinoma; AC, adenocarcinoma; ASC, adenosquamous carcinoma. Data are the mean (SD) or N (%). aThe p-values was calculated using a Spearman’s correlation analysis b The p-values was calculated using a Pearson chi-square test.