Table 5.
Multivariable Adjusted Cox Proportional Hazards Models * for the Association †‡ of Allostatic Load Score with All-Cause and Cancer-Specific Mortality in REGARDS Stratified by Age Group (N = 29,700).
| Allostatic Load | Age < 65 years (N = 15,008) † | Age ≥65 years (N = 14,692) † | ||
|---|---|---|---|---|
| All-Cause mortality ‡ | Cancer mortality ‡ | All-Cause mortality ‡ | Cancer mortality ‡ | |
| Deaths | 1106 | 320 | 3556 | 917 |
| Crude | 1.47 (1.42, 1.53) | 1.17 (1.09, 1.26) | 1.28 (1.25, 1.31) | 1.11 (1.06, 1.16) |
| Model 1 * | 1.46 (1.40, 1.51) | 1.15 (1.07, 1.24) | 1.27 (1.24, 1.30) | 1.10 (1.05, 1.15) |
| Model 2 * | 1.43 (1.37, 1.49) | 1.13 (1.04, 1.22) | 1.26 (1.23, 1.29) | 1.10 (1.05, 1.15) |
| Model 3 * | 1.36 (1.31,1.42) | 1.07(0.99, 1.16) | 1.24 (1.21, 1.27) | 1.08 (1.03, 1.13) |
| Model 4 * | 1.34 (1.28, 1.39) | 1.06 (0.98, 1.15) | 1.22 (1.19, 1.25) | 1.07 (1.02, 1.12) |
* All models included allostatic load score as main covariate. Model 1 additionally adjusted for age at baseline, model 2 further adjusted for race, model 3 further adjusted for sex, education, and income. † Analysis was stratified by age < 65 years and ≥65 years. ‡ Results presented as HRs and 95% CI. Bold text p-values are below the selected two-sided alpha of 0.05.