Table 1.

Senescence-associated secretory phenotype (SASP) factors significantly induced by overexpression of miR-34a in HASMCs.

SASP Factors
Interleukins/chemokines	GRO-α, I-309, IL6, IL10, IL12, IL13, PARC, MIP-1δ
Growth factors/regulators	IGFBP-3, PIGF
Metallopeptidase inhibitor	TIMP-2

GRO-alfa = Growth-Regulated Oncogene-alfa; I-309 = human cytokine I-309; IL6 = Interleukin 6; IL10 = Interleukin 10; IL12 = Interleukin 12; IL13 = Interleukin 13; MIG = Monokine Induced by gamma Interferon; MIP-1 δ = Macrophage Inflammatory Proteins-1 delta; IGFBP-3 = Insulin-like Growth Factor Binding Protein 3; PARC = Pulmonary and activation-regulated chemokine; PIGF = Placental growth factor; TIMP-2 = Metallopeptidase Inhibitor 2.