BC	breast cancer
CCK-8	cell counting kit-8
CTRL	control
DAB	3,3′-diaminobenzidine tetrahydrochloride
DAPI	4′,6-diamidino-2-phenyindole, dilactate
DMEM	Dulbecco’s modification of Eagle medium
EC	endothelial cell
ECL	enhanced chemiluminescence
ER	estrogen receptors
ERK	extracellular-signal-regulated kinase
ESM-1	endothelial cell-specific molecule 1
EV	empty vector
FBS	fetal bovine serum
HER2	human epidermal growth factor receptor 2
HIF-1α	hypoxia-inducible factor 1 alpha
ICAM-1	intercellular adhesion molecule-1
IFNγ	interferon gamma
IHC	immunohistochemistry
IL-1β	interleukin 1 beta
MDA-MB-231 BR	MDA-MB-231 cells with a brain metastatic phenotype
MMP	matrix metalloproteinase
NF-κB	nuclear factor kappa B
PDK1	phosphoinoisitide dependent kinase 1
PI3K	phosphoinositide 3-kinase
PKC	protein kinase C
PR	progesterone receptors
P2Y2R	P2Y purinergic receptor 2
RT-PCR	reverse transcription-polymerase chain reaction
RT	radiotherapy
RT-R	radiotherapy resistant
SD	standard deviation
SDS-PAGE	sodium dodecyl sulfate-polyacrylamide gel electrophoresis
siRNA	small interfering RNA
STAT-3	signal transducer and activator of transcription 3
TNBC	triple negative breast cancer
TNFα	tumor necrosis factor alpha
VCAM-1	vascular cell adhesion molecule-1
VEGF	vascular endothelial growth factor