Figure 5.
FLASH-RT preserves the neurogenic niche. Immature neurons (doublecortin, DCX+) were quantified using unbiased stereology 4 months post-irradiation of juvenile mice. Compared to controls (A) and FLASH-RT (B), CONV-RT (C) leads to a significant decline in the DCX+ immature neurons (D). Mean ± s.e.m. (n = 4 animals per group), p values were compared against CONV and derived from ANOVA and Bonferroni’s multiple comparisons test. ** p < 0.01, * p < 0.05. Scale bar: 10 μm, (A–C).