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. 2020 Jun 18;12(6):1611. doi: 10.3390/cancers12061611

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Snail is essential for arecoline-induced myofibroblast transdifferentiation. (A) Relative gene and (B) protein expression levels of Snail in arecoline-treated BMFs with sh-Luc or sh-Snail; myofibroblast activities, including (C) collagen gel contraction, (D) migration and (E) invasion abilities of arecoline-treated BMFs with sh-Luc or sh-Snail. The area of the gel is indicated by the green dotted line. Results are means ± SD of triplicate samples from three experiments. * p < 0.05 compared to sh-Luc group. ^# p < 0.05 compared to arecoline+ sh-Luc group.