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. 2020 May 26;12(6):1368. doi: 10.3390/cancers12061368

Table 3.

Subgroup analysis.

Subgroup Colorectal Cancer p for Interaction Colon Cancer p for Interaction Rectal Cancer p for Interaction
Age (years) 0.102 0.024 0.959
<65 1.07 (1.05–1.09) 1.08 (1.05–1.10) 1.05 (1.02–1.09)
≥65 1.15 (1.13–1.18) 1.18 (1.15–1.20) 1.11 (1.06–1.15)
Sex <0.001 <0.001 0.003
Male 1.15 (1.13–1.17) 1.17 (1.15–1.20) 1.09 (1.06–1.13)
Female 1.11 (1.08–1.13) 1.11 (1.08–1.14) 1.09 (1.04–1.14)
Diabetes mellitus 0.003 0.003 0.041
No 1.11 (1.09–1.12) 1.12 (1.10–1.14) 1.09 (1.05–1.12)
Yes 1.08 (1.05–1.11) 1.09 (1.05–1.13) 1.04 (0.99–1.10)
Body mass index (kg/m2) 0.037 0.016 0.738
<25 1.07 (1.04–1.10) 1.07 (1.04–1.10) 1.07 (1.02–1.12)
≥25 1.10 (1.07–1.12) 1.10 (1.08–1.13) 1.08 (1.03–1.12)
Smoking 0.331 0.340 0.444
Non-smoker 1.12 (1.10–1.14) 1.13 (1.11–1.15) 1.09 (1.06–1.12)
Current smoker 1.09 (1.05–1.12) 1.09 (1.06–1.13) 1.08 (1.03–1.14)

Hazard ratio (95% confidence interval) was calculated using multivariable Cox regression analysis after adjusting for age, sex, smoking status, alcohol consumption, physical activity, income, hypertension, diabetes mellitus, and dyslipidemia.