Table 3.
Subgroup | Colorectal Cancer | p for Interaction | Colon Cancer | p for Interaction | Rectal Cancer | p for Interaction |
---|---|---|---|---|---|---|
Age (years) | 0.102 | 0.024 | 0.959 | |||
<65 | 1.07 (1.05–1.09) | 1.08 (1.05–1.10) | 1.05 (1.02–1.09) | |||
≥65 | 1.15 (1.13–1.18) | 1.18 (1.15–1.20) | 1.11 (1.06–1.15) | |||
Sex | <0.001 | <0.001 | 0.003 | |||
Male | 1.15 (1.13–1.17) | 1.17 (1.15–1.20) | 1.09 (1.06–1.13) | |||
Female | 1.11 (1.08–1.13) | 1.11 (1.08–1.14) | 1.09 (1.04–1.14) | |||
Diabetes mellitus | 0.003 | 0.003 | 0.041 | |||
No | 1.11 (1.09–1.12) | 1.12 (1.10–1.14) | 1.09 (1.05–1.12) | |||
Yes | 1.08 (1.05–1.11) | 1.09 (1.05–1.13) | 1.04 (0.99–1.10) | |||
Body mass index (kg/m2) | 0.037 | 0.016 | 0.738 | |||
<25 | 1.07 (1.04–1.10) | 1.07 (1.04–1.10) | 1.07 (1.02–1.12) | |||
≥25 | 1.10 (1.07–1.12) | 1.10 (1.08–1.13) | 1.08 (1.03–1.12) | |||
Smoking | 0.331 | 0.340 | 0.444 | |||
Non-smoker | 1.12 (1.10–1.14) | 1.13 (1.11–1.15) | 1.09 (1.06–1.12) | |||
Current smoker | 1.09 (1.05–1.12) | 1.09 (1.06–1.13) | 1.08 (1.03–1.14) |
Hazard ratio (95% confidence interval) was calculated using multivariable Cox regression analysis after adjusting for age, sex, smoking status, alcohol consumption, physical activity, income, hypertension, diabetes mellitus, and dyslipidemia.