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. 2020 May 31;12(6):1428. doi: 10.3390/cancers12061428

Table 2.

Patient characteristics of conversion surgery.

Variables n = 32 UR-LA (n = 17) UR-M (n = 15) p-Value
Age(years), median (range) 66 (36–84) 65 (38–75) 69 (50–83) 0.135
Male: Female, n (%) 14 (44): 18 (56) 7(41):10(59) 7(47):8(53) 0.754
Ph: Pbt, n (%) 14 (44): 18 (56) 9 (53): 8 (47) 5 (33): 10 (67) 0.264
Tumor Size(mm), median (range) 36 (25–74) 35 (25–55) 40 (27–74) 0.747
Mets site: None:L:P, n (%) 17 (53): 4 (13):11 (34) 17 (100): 0 (0):0 (0) 0(0): 4 (27):11 (73) <0.0001
CA19-9; U/mL, median (range) 278 (1.2–3400) 126 (8.4–2200) 984 (6.6–1953) 0.209
Preoperative CA19-9 29.1(1.0–181.9) 39.7(1.0–181.9) 19(1.0–73.9) 0.42
Primary Treatment
GEM or GS 7 4 3
GEM + nab-PTX (GnP) 7 4 3
S1 or GEM based + ip PTX 8 0 8
FOLFIRINOX 3 3 0
GEM or S-1 or GS + RT (50.4 Gy) 7 6 1
Radiation, n (%) 13(41) 11(65) 2(13) 0.002
Pretreatment period to op; (median, range) 9.5(4–28) 10 (4–28) 9 (6–16) 0.6207
RECIST (CR: PR), n (%) 1 (3.1%): 31(96.9%) 0(0):17(100) 1(7):14(63) 0.153
Operative time(min) 454(223–866) 441(223–655) 467(227–866) 0.36
Intraoperative blood loss(mL) 1229(207–6301) 1087(237–2931) 1255(207–6301) 0.58
Blood transfusion (U) 0(0–12) 0(0–7) 0(0–12) 0.42
PD: DP: DP-CAR: TP, n (%) 13 (40): 11(34): 4(13): 4(13) 9(52):4(24):2(12):2(12) 5(33):7(47):2(13):1(7) 0.257
-CHA/CA/PV resection- -3(9)/4(13)/15(47)- -3(18)/2(12)/9(52)- -0(0)/2(13)/6(40)-
Residual tumor (R0: R1), n (%) 29(91): 3(9) 16(94):1(6) 13(87):2(13) 0.471
Postop comp/Mortality (%) 8(25)/0(0) 2(12)/0(0) 6(40)/0(0) 0.066/0
Hospital stay (median, range) 14 (7–114) 11 (7–41) 14 (7–114) 0.271
Evans (I/IIa/IIb/III/IV, (%)) 1(3)/12(38)/10(31)/8(25)/1 (3) 1(6)/7(41)/5(29)/4(24)/0 (0) 0(0)/5(33)/5(33)/4 (27)/1(7) 0.695

Ph: pancreas head, Pbt: pancreas body and tail, Mets: metastasis, L: liver, P: peritoneum, GEM: gemcitabine, GS: S-1 combined with gemcitabine, GnP: nab-paclitaxel combined with gemcitabine, PTX: paclitaxel, RT: radiation, PD: pancreaticoduodenectomy, DP: distal pancreatectomy, DP-CAR: distal pancreatectomy with en-bloc celiac axis resection, CHA: common hepatic artery, CA: celiac artery, PV: portal vein.