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. 2020 Jun 21;12(6):1644. doi: 10.3390/cancers12061644

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Proteomic analysis of bile from patients with benign stenoses and patients with CCA. (a) Pie chart showing the classification of proteins according to their cellular localization. (b) Volcano plot (−log10 [p-value] and log2 [fold-change]) of the proteins found in bile from patients with CCA compared with patients with benign stenoses. (c) Ingenuity pathway analysis (IPA) of the differentially represented proteins between control and CCA bile samples identifying the top enriched categories of canonical pathways.