ICIs |
immune checkpoint inhibitors |
CTLA-4 |
cytotoxic T lymphocyte antigen-4 |
PD-1 |
programmed cell death protein 1 |
FDA |
the US food and drug administration |
NSCLS |
non-small cell lung cancer |
SCLS |
small cell lung cancer |
RCC |
renal cell carcinoma |
HNC |
head and neck cancer |
UC |
urothelial carcinoma |
CRC |
colorectal cancer |
ORR |
overall response rate |
TKIs |
tyrosine kinase inhibitors |
STRs |
short tandem repeats |
MSI |
microsatellite instability |
MMR |
mismatch repair |
LD-SCLC |
limited disease SCLC |
ED-SCLC |
extensive-disease SCLC |
OS |
overall survival |
MDSCs |
myeloid-derived suppressor cells |
EC |
esophageal cancer |
HCC |
hepatocellular carcinoma |
MTD |
maximum tolerated dose |
CR |
complete response |
PR |
partial response |
mPFS |
median progression-free survival |
HNC |
head and neck cancer |
UC |
urothelial carcinoma |
UBC |
urinary bladder cancer |
UTUC |
upper tract urothelial carcinoma |
irAEs |
immune-related adverse effects |