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. 2020 Jun 22;21(12):4427. doi: 10.3390/ijms21124427
ICIs immune checkpoint inhibitors
CTLA-4 cytotoxic T lymphocyte antigen-4
PD-1 programmed cell death protein 1
FDA the US food and drug administration
NSCLS non-small cell lung cancer
SCLS small cell lung cancer
RCC renal cell carcinoma
HNC head and neck cancer
UC urothelial carcinoma
CRC colorectal cancer
ORR overall response rate
TKIs tyrosine kinase inhibitors
STRs short tandem repeats
MSI microsatellite instability
MMR mismatch repair
LD-SCLC limited disease SCLC
ED-SCLC extensive-disease SCLC
OS overall survival
MDSCs myeloid-derived suppressor cells
EC esophageal cancer
HCC hepatocellular carcinoma
MTD maximum tolerated dose
CR complete response
PR partial response
mPFS median progression-free survival
HNC head and neck cancer
UC urothelial carcinoma
UBC urinary bladder cancer
UTUC upper tract urothelial carcinoma
irAEs immune-related adverse effects