Figure 5.
Analysis of neutrophil-related signature genes in the different breast cancer subtypes. RNA seq values (Fragments Per Kilobase Million, FPKM) of 1100 breast cancer samples, deposited in The Cancer Genome Atlas (TCGA) database, were stratified into Luminal A (lumA), Luminal B (lumB), HER2+ (HER2), and Basal subtypes. Genes analyzed: MPO (myeloperoxidase), DEFA1B (a-defensin 1B), MMP8 (MMP8), CEACAM8 (CD66b), LTF (lactotransferrin), and DEFA4 (a-defensin 4). The Mann–Whitney U test was used to test for statistical significance. * p < 0.05, ** p < 0.01, *** p < 0.001, and n.s.: no significance.
