Table 3.
Histopathological parameters measured as percentage of pigs with cryptitis, crypt abscesses, erosion/ulceration and the overall inflammation score in the proximal (Co25), mid (Co50) or distal (Co75) colon after five days of DSS or placebo treatment in pigs fed the control (C) or the meat (M) diet (n = 6/group, except C-DSS n = 5). Least square mean values with their standard errors.
| Treatment | p-Value | |||||||
|---|---|---|---|---|---|---|---|---|
| C | M | C-DSS | M-DSS | SEM | Diet | DSS | D × DSS | |
| Co25 | ||||||||
| Cryptitis, % | 67 | 67 | 61 | 75 | 22 | 0.74 | 0.95 | 0.74 |
| Crypt abscess, % | 67 | 50 | 100 | 83 | 21 | 0.40 | 0.11 | 1.00 |
| Erosion/Ulceration, % | 0 b | 0 b | 37 a | 33 a | 16 | 0.90 | 0.03 | 0.90 |
| Inflammation score | 0.75 b | 0.58 b | 1.9 a | 1.9 a | 0.4 | 0.86 | <0.01 | 0.76 |
| Co50 | ||||||||
| Cryptitis, % | 67 ab | 33 b | 63 ab | 100 a | 19 | 0.90 | 0.08 | 0.05 |
| Crypt abscess, % | 83 | 83 | 100 | 100 | 14 | 0.97 | 0.22 | 0.97 |
| Erosion/Ulceration, % | 0 c | 0 c | 40 b | 83 a | 13 | 0.10 | <0.001 | 0.10 |
| Inflammation, score | 0.75 c | 0.50 c | 1.9 b | 2.7 a | 0.2 | 0.18 | <0.001 | 0.01 |
| Co75 | ||||||||
| Cryptitis, % | 33 | 50 | 74 | 83 | 20 | 0.49 | 0.06 | 0.84 |
| Crypt abscess, % | 50 b | 67 b | 94 a | 100 a | 14 | 0.39 | <0.01 | 0.70 |
| Erosion/Ulceration, % | 0 c | 0 c | 40 b | 83 a | 13 | 0.10 | <0.001 | 0.10 |
| Inflammation, score | 0.50 c | 0.58 c | 1.7 b | 2.5 a | 0.3 | 0.06 | <0.001 | 0.13 |
a,b,c Means within a row with unlike superscript letters were significantly different (p ≤ 0.05).