Table A2.

Mean escape time (τ) of a given molecule, errors and total traveling distance of the confined molecule in a spherical cavity (cavity diameter 10² nm and 10³ nm) for different entrance–escape hole diameters (h) calculated by the diffusion and the non-interactive random walk models.

h (nm)	Cavity Diameter D = 102 nm					Cavity Diameter D = 103 nm
	Diffusion	Random Walk				Diffusion	Random Walk
	τ (s)	τ (s)	Error (s)	Distance (nm)	Error (nm)	τ (s)	τ (s)	Error (s)	Distance (nm)	Error (nm)
0.3	3.98 × 10−8	5.71 × 10−5	1.8 × 10−6	3.68 × 107	1.2 × 106	3.98 × 10−5	5.3 × 10−2	1.7 × 10−3	3.42 × 1010	1.1 × 109
0.5	2.39 × 10−8	2.00 × 10−5	6 × 10−7	1.29 × 107	4.1 × 105	2.39 × 10−5	2.01 × 10−2	6.3 × 10−4	1.3 × 1010	4.1 × 108
1	1.19 × 10−8	4.63 × 10−6	1.4 × 10−7	2.99 × 106	9 × 104	1.19 × 10−5	5.43 × 10−3	1.6 × 10−4	3.5 × 109	1.1 × 108
2	5.98 × 10−9	1.22 × 10−6	4 × 10−8	7.89 × 105	2.5 × 104	5.98 × 10−6	1.33 × 10−3	4.1 × 10−5	8.56 × 108	2.7 × 107
5	2.39 × 10−9	1.95 × 10−7	6 × 10−9	1.26 × 105	4 × 103	2.39 × 10−6	1.92 × 10−4	6.7 × 10−6	1.24 × 108	4.3 × 106
10	1.19 × 10−9	5.18 × 10−8	1.6 × 10−9	3.34 × 104	1060	1.19 × 10−6	4.99 × 10−5	1.6 × 10−6	3.22 × 107	1.1 × 106
20	5.97 × 10−10	1.21 × 10−8	3 × 10−10	7821	244	5.97 × 10−7	1.23 × 10−5	4.1 × 10−7	7.93 × 107	2.6 × 105
50	2.39 × 10−10	1.87 × 10−9	5 × 10−11	1204	35	2.39 × 10−7	1.99 × 10−6	6.4 × 10−8	1.28 × 106	4.1 × 104
100						1.19 × 10−7	5.07 × 10−7	1.5 × 10−8	3.27 × 105	9.8 × 103
200						5.97 × 10−8	1.25 × 10−7	3.7 × 10−9	8.05 × 104	2.4 × 103
500						2.39 × 10−8	1.88 × 10−8	5.6 × 10−10	1.21 × 104	3.6 × 102