Table 3.
Correlation coefficients and p-values for relationships between changes in astaxanthin level, inflammatory and oxidative stress markers, and cardiac functions from baseline to 3 months.
| %ΔLVEF | %ΔLVEDVI | %ΔLVESVI | %ΔE/e’ | %ΔRVSP | %ΔBNP | %Δ6MWD | |
|---|---|---|---|---|---|---|---|
| Δastaxanthin | 0.138 p = 0.592 |
−0.044 p = 0.864 |
−0.053 p = 0.838 |
0.324 p = 0.210 |
0.454 p = 0.079 |
0.097 p = 0.707 |
−0.126 p = 0.624 |
| %ΔTNF-α | −0.134 p = 0.620 |
−0.216 p = 0.421 |
−0.119 p = 0.662 |
0.042 p = 0.878 |
−0.395 p = 0.130 |
−0.268 p = 0.316 |
0.441 p = 0.088 |
| %ΔCRP | −0.397 p = 0.152 |
0.090 p = 0.745 |
0.237 p = 0.393 |
−0.307 p = 0.269 |
0.062 p = 0.823 |
0.237 p = 0.393 |
−0.230 p = 0.407 |
| %ΔdROM | −0.509 p = 0.049 |
0.706 p = 0.006 |
0.774 p = 0.003 |
0.309 p = 0.232 |
0.354 p = 0.170 |
0.276 p = 0.284 |
−0.015 p = 0.955 |
| %ΔBAP | −0.021 p = 0.936 |
−0.071 p = 0.785 |
−0.015 p = 0.955 |
−0.362 p = 0.161 |
−0.454 p = 0.079 |
−0.238 p = 0.356 |
0.306 p = 0.236 |
| %Δ8-OHdG | 0.006 p = 0.983 |
−0.033 p = 0.904 |
−0.004 p = 0.989 |
−0.213 p = 0.428 |
0.102 p = 0.706 |
0.266 p = 0.320 |
0.148 p = 0.585 |
BAP, biological antioxidant potential; BNP, B-type natriuretic peptide; CRP, C-reactive protein; dROM, diacron reactive oxygen metabolites; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; LVEDVI, left ventricular end-diastolic volume index; LVEF, left ventricular ejection fraction; LVESVI, left ventricular end-systolic volume index; RVSP, right ventricular systolic pressure; 6MWD, six minute walk distance; TNF, tumor necrotic factor.