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. 2020 Jun 24;12(6):1880. doi: 10.3390/nu12061880

Table 2.

Mean absolute changes (95% confidence intervals) from baseline to six weeks for total calories (kcal/day), macronutrients (carbohydrate, fat, protein; grams/day) and relative protein (g/kg body mass).

Creatine (n = 9) Placebo (n = 8) Time Group Interaction d
p-Value p-Value p-Value
Total calories −515.6 (−838.1, −193.1) * −17.1 (−285.4, 251.1) 0.011 0.861 0.016 0.72
Carbohydrate −39.3 (−81.5, 2.9) −4.6 (−29.5, 20.4) 0.063 0.84 0.134 0.39
Fat −33.4 (−69.0, 2.2) 1.7 (−21.4, 24.8) 0.113 0.786 0.082 0.84
Protein −14.5 (−33.1, 4.2) −3.5 (−18.3, 11.3) 0.105 0.82 0.311 0.19
Relative protein −0.18 (−0.40, 0.03) −0.03 (−0.22, 0.14) 0.104 0.255 0.265 0.32

* Creatine significantly different than placebo (p < 0.05). d = effect size.