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Changes in hepatic damage-associated diagnostic markers. (A) Aspartate aminotransferase (AST) and total bilirubin. (B) Total bile acid. Mice were supplemented with 0.3-mg Se/kg selenoneine for 4 months. Values are presented as mean ± SD (n = 8). Significant differences were assessed using Student’s t-test (*, p < 0.05 vs. corresponding control mice).
