Table 3.

Hepatic mRNA levels of selenoprotein and lipid-related genes.

Gene Symbol	Control	Selenoneine
Acc1	1.00 ± 0.60	0.53 ± 0.42 *
Scd1	1.00 ± 0.55	0.24 ± 0.22 **
Fasn	1.00 ± 0.86	0.34 ± 0.26 *
Ppar α	1.00 ± 0.77	0.79 ± 0.54
Srebp1c	1.00 ± 0.67	0.47 ± 0.54
Bsep	1.00 ± 0.71	0.47 ± 0.34
Cyp7a1	1.00 ± 0.60	1.77 ± 1.47
Gpx1	1.00 ± 0.86	0.34 ± 0.35 *
Gpx2	1.00 ± 1.97	1.01 ± 1.65
Gpx4	1.00 ± 0.66	0.46 ± 0.50
Txnrd1	1.00 ± 0.78	0.49 ± 0.49
Selenop	1.00 ± 0.86	0.38 ± 0.34 *

Scd1, stearoy-CoA desaturase-1; Acc1, acetyle-CoA carboxylase-1; Fasn, fatty acid synthase; Pparα, peroxisome proliferator-activated receptor; Srebp1c, sterol regulatory element binding protein 1c; CYP7α1, cholesterol 7α-hydroxylase; Bsep, bile salt export pump; Gpx1, glutathione peroxidase 1; Selenop: selenoprotein P, Txnrd1: thioredoxin reductase 1. Values are presented as mean ± SD (n = 8). Significant differences were assessed by the Student’s t-test (*, p < 0.05; **, p < 0.01).