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. 2020 Jun 16;12(6):1789. doi: 10.3390/nu12061789

Table 7.

Overview of the anti-pathogenic functionalities of POS.

POS Characteristics + Source [POS] Strains Used Observed Effects References
Mw 1–4 kDa Citrus (high methylation)
Apple (low methylation)
10 mg/mL Gram-negative:Escherichia coli O157:H7 Shiga toxin Inhibition of host cell infiltration of Stx [185]
Mw 1–12 kDa Panax ginseng 0.01–0.5 mg/mL Gram-negative: Aggregatibacter actinomycetemcomitans
Gram-positive: Staphylococcus aureus
Anti-adhesive effect [189]
DP 2–3 Orange peel 2.5 mg/mL Gram-negative: EPEC, VTEC, Desulfovibrio desulfuricans Anti-adhesive effect [186]
GalA:Rhamnose 1:1 Albedo of orange peel 0.05–2.5 mg/mL Gram-negative: Campylobacter jejuni Inhibited Caco-2 cell invasion [177]
0.2–6 kDa 93.6% Uronic acid Haw 1–10 mg/mL Gram-negative: Escherichia coli Antimicrobial activity dependent on concentration and low pH [178]
DP 6–19 Orange peel 1–100 mg/mL Gram-negative:Escherichia coli
Gram-positive:Staphylococcus aureus, Bacillus subtilis
Antimicrobial activity-low Mw more effective [176]
Apple, citrus, polygalacturonic acid 0.1 mg/mL Gram-negative: Escherichia coli
Gram-positive: Staphylococcus aureus
Growth inhibition, potentially through CO2 radical production [184]
Mw 9–73 kDa Orange peel 0.005–5 mg/mL Gram-negative: Shigatoxigenic Escherichia coli Anti-adhesive effect, direct interaction with Stx [188]