Figure 5.

Effects of high-fat diet (HFD) and AP-NHm 1–2, in co-treatment or in post-injury treatment, (a) on body weight from Day 0 and (b) on food intake from Day 42 to Day 84. Mice were fed with normal or HFD diet from Day 0 to Day 84: two groups were co-treated with AP-NHm while other two groups started AP-NHm treatment on Day 49. Control groups were treated with vehicle throughout the study. Each value represents the mean ± SEM of 12 mice per group. ** p < 0.01 vs. standard diet + vehicle, ^^ p < 0.01 vs. HFD + vehicle.