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. 2020 Jun 18;12(6):1815. doi: 10.3390/nu12061815

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Alpha-diversity index of the gut microbiota in the subjects with depression symptoms (depression) and flavonoid-rich orange juice (FR) or equicaloric flavonoid-low orange cordial (FL) treatment groups: (A) Chao 1, (B) phylogenic diversity, (C) Shannon, and (D) Simpson. Box plots depict greater gut microbial diversity in the flavonoid-rich orange juice (FR) group than in the depression symptoms group (Depression; the participants of baseline before intervention) or flavonoid-low orange cordial (FL), according to the Shannon and Simpson indexes. The horizontal lines in the box plots represent median values; upper (Q3) and lower (Q1) ranges of the box represent the 75% and 25% quartiles, respectively.