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. 2020 Jun 11;12(6):1749. doi: 10.3390/nu12061749

Figure 2.

Figure 2

Figure 2

(-)-Oleocanthal selectively inhibited the viability of A549 and NCI-H322M LC cell lines and minimally affected the non-tumorigenic human microvascular endothelial cells viability. Effects of Oleocanthal (OC) treatment against the growth of A549 (A) and NCI-H322M (B) LC cells in the presence or absence of 40 ng/mL mitogenic HGF over 48 h treatment period. (C) Effects of OC treatment on the viability of the non-tumorigenic human microvascular endothelial cells (HMVEC) over 48 h treatment period. Cells were plated at a density of 1 × 104 cells per well in 96-well plates and maintained in media supplemented with 10% fetal bovine serum (FBS) and allowed to adhere overnight. The next day, cells were washed with phosphate-buffered saline (PBS), divided into HGF or no HGF treatment groups. Viable cells count was determined by MTT assay at 48 h. Vertical bars indicate the mean cell count ±SD in each treatment group. a p < 0.05 significantly different compared to vehicle-treated control without HGF and b p < 0.05 significantly different compared to vehicle-treated control with HGF 40 ng/mL over 48 h.