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. 2020 Jun 16;12(6):1790. doi: 10.3390/nu12061790

(A)

Authors & Year Study Design Population Intervention Analyzed Results Main Conclusions
Savory et al., 2012 [19] Placebo-controlled, double-blind, crossover 20 healthy subjects 9♂ & 1♀
NW: 4 ♂ & 6 ♀
27.9 ± 2.2 y
BMI 22.8 ± 0.4 kg/m2
OW: 5 ♂ & 5 ♀
31.4 ± 1.9 y
BMI 28.0 ± 0.8 kg/m2 		Supplementation: 200 μg Se (sodium selenite) once per day * 3 weeks’ placebo (not containing glucose) during another 3-week period.
Washout period 2 moth.
Order treatment: NW: Se/Placebo OW: Placebo/Se
14-week total period
PhA: test 30 min treadmill session at 70% VO2peak		 [Se] Post Se treatment period ↑ *[Se] NW & OW compared to week 0
Post Se treatment period ↑* [Se] NW & OW compared to placebo treatment
TAS, GSH, SOD Placebo period & Se treatment period
  • -

    rest vs. post PhA: OW & NW ↔ TAS; GSH; SOD

  • -

    OW vs. NW ↔ TAS; GSH; SOD
LH Placebo period
  • -

    rest vs. post PhA: OW ↑*LH NW ↑LH

  • -

    OW vs. NW ↑*LH
Se treatment period
  • -

    rest vs. post PhA: OW †LH NW †LH

  • − OW vs. NW †LH

Placebo vs. Se treatment post PhA: OW ↓*LH; NW↔LH
Tessier et al., 1994 [26] Placebo-controlled, double-blind, randomized 24 ♂ healthy students
22.9 ± 2.1 y;
8.0 ± 8.7 Kg;
178.0 ± 6.6 cm;
Body fat 11.2 ± 4.4 %
PbG n = 12 ♂
22.5 ± 2.0 y;
67.3 ±7.0 Kg;
177.4 ± 7.0 cm;
Body fat 10.4 ± 3.9 %
SeG n = 12 ♂
23.2 ± 2.3 y;
68.7 ± 10.4 Kg;
178.7 ± 6.3 cm;
Body fat 12.3 ± 4.8 %		 Supplementation: 180 μg Se (Seleniomethionine) once per day * 10-week period
PhA: 10-week endurance training program 4-week nontraining
 Pre-PhA vs. Post-PhA SeG vs. PbG
[Se] ↑*[Se] SeG ↓[Se] PbG # [Se]
GTtotal ↓* SeGr ↓* PbGr † GTtotal
GSSG ↓ GSSG SeGr ↓ GSSG PbGr † GSSG
GPx plasma ↑* SeG ↑PbG # GPx
EGPx ↑* SeG ↑PbG # EGPx
EGR ↑* SeG ↑*PbG † EGR
Vitamin E ↓SeG ↑PbG † Vitamin E
VO2max ↑* SeG ↑*PbG † VO2max
SeG: ↑ VO2max positive correlated ↑GPX (r:0.66 p < 0.05 n = 12)