Table 1.
Results of longitudinal analysis on tumor zize. Tumor size was analyzed as a function of log(time), log(time)2, sex, age at irradiation, tumor volume at irradiation, radiation energy and nanoparticle size, with sex = M, energy = 90 kVp, and size = smallest being the reference level. A positive (negative) estimate indicates that a larger (smaller) value of the parameter is associated with a larger tumor size than the reference level. A p-value < 0.05 is considered statistically significant. Results show that every variable had a statistically significant effect on the tumor size, although the middle and smallest sizes were not different by a statistically significant amount.
| Parameter Estimates for Response Model | ||||
|---|---|---|---|---|
| Parameter | Estimate | Standard Error | p Value | |
| Intercept | −0.8984 | 0.1490 | <0.0001 | |
| Log(time) | −1.5387 | 0.1143 | <0.0001 | |
| Log(time)2 | 0.6422 | 0.0446 | <0.0001 | |
| Sex | F | 0.3136 | 0.1465 | 0.0323 |
| Sex | M | 0 | - | - |
| Age at Irradiation | −0.2552 | 0.0545 | <0.0001 | |
| Tumor Volume at Irradiation | 0.3751 | 0.0814 | <0.0001 | |
| Energy | 250 kVp | 0.8810 | 0.2854 | 0.0020 |
| Energy | 350 kVp | 1.8928 | 0.2220 | <0.0001 |
| Energy | 90 kVp | 0 | - | - |
| Size | Middle | 0.1599 | 0.1678 | 0.3407 |
| Size | Largest | 0.6183 | 0.1864 | 0.0009 |
| Size | Smallest | 0 | - | - |