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. 2020 Apr 2;11(2):22. doi: 10.3390/jfb11020022

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Concentration–response curves for cisplatin, DM-EVs, PD-EVs, and the combination of DM-EVs and PD-EVs against breast and skin tumor cells. (a–d) Cytotoxicity of cisplatin (a), DM-EVs (b), PD-EVs (c), and DM-EVs + PD-EVs (d) against human breast cells. (e–h) Cytotoxicity of cisplatin (e), DM-EVs (f), PD-EVs (g), and DM-EVs + PD-EVs (h) against human skin cells. (i) half-maximal inhibitory concentration (IC₅₀) values of cisplatin, DM-EVs, PD-EVs, and the combination of DM-EVs and PD-EVs for breast and skin cells. Cisplatin was used as a positive control.