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. 2020 May 26;9(6):688. doi: 10.3390/foods9060688

Figure 2.

Figure 2

Effects of taurine on transcriptional expression of thermogenesis-related genes in tissues. (A) The basal mRNA expression levels of PGC-1α, Cox7a1, Cox8b, UCP-1, and CIDE-A were compared to determine the relative expression of the genes from the three tissues in the normal diet fed (N) group: inguinal white fat tissue (iWAT), interscapular brown fat tissue (BAT), and quadricep muscle tissues. (B) The mRNA expression levels of the genes in iWAT, BAT, and muscles of the three groups were compared to determine how HFD and/or taurine supplementation affected the gene expression of each tissue of the three groups; N normal diet group (n = 5), HFD high-fat diet group (n = 5), and H + Tau HFD + taurine (2% in drinking water) group (n = 5). Differences between the three groups were analyzed using the nonparametric Kruskal–Wallis test. If a statistical difference was detected (p < 0.05), post hoc pairwise group comparisons were performed using Dunn’s test with Bonferroni multiple-testing correction. The P values of the two groups were included to show the expression difference of thermogenesis-related genes. Differences were considered statistically significant at p < 0.05. ** p < 0.01; * p < 0.05; ns not significant. N normal diet group, HFD high-fat diet group, H + Tau HFD + taurine (2% in drinking water) group.