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Expression of LMP-2 in spontaneously hypertensive rats. Data show the increase in blood pressure during ageing (A), the increase in heart weight to tibia length (HW/TL) as a parameter of hypertrophy (B), the induction of atrial natriuretic peptide (ANP; C), and the mRNA expression of LMP-2 (D) in the animals after 1.5–7.0 months as indicated. Data are means ± SD from n = 6 rats. *; p < 0.05 vs. 1.5 months.
