Table 4.
Body weights of embryos and dams and the chow intake and litter size of dams
| Ethanol | |||
| Untreated | Control | Ethanol | |
| Body weight—E19 (g) | 6.670 ± 0.39 | 6.120 ± 0.16 | 6.310 ± 0.19 |
| Body weight—dams (g) | 295.5 ± 8.5 | 285.0 ± 12.3 | 282.1 ± 10.3 |
| Chow intake (kcal/day) | 71.90 ± 2.9 | 70.70 ± 3.2 | 65.40 ± 3.4 |
| Litter size | 11.70 ± 1.0 | 12.40 ± 0.7 | 12.70 ± 0.6 |
| CCL2 | |||
| Untreated | Control | CCL2 | |
| Body weight—E19 (g) | 6.200 ± 0.28 | 6.000 ± 0.17 | 6.040 ± 0.18 |
| Body weight—dams (g) | 292.1 ± 7.4 | 277.3 ± 5.0 | 279.1 ± 6.5 |
| Chow intake (kcal/day) | 66.70 ± 4.1 | 68.40 ± 3.2 | 64.10 ± 4.4 |
| Litter size | 11.70 ± 1.2 | 12.40 ± 0.7 | 12.70 ± 0.6 |
| Ethanol + INCB | |||
| Control | Ethanol | Ethanol + INCB3344 | |
| Body weight—E19 (g) | 6.290 ± 0.23 | 6.070 ± 0.23 | 6.160 ± 0.13 |
| Body weight—dams (g) | 280.3 ± 8.7 | 273.9 ± 11.0 | 282.7 ± 9.1 |
| Chow intake (kcal/day) | 75.30 ± 4.7 | 72.20 ± 3.0 | 69.50 ± 2.7 |
| Litter size | 11.30 ± 1.0 | 11.60 ± 1.3 | 11.00 ± 1.2 |
Data are mean ± SEM. n = 7/group, *p < 0.05 versus control. Two-way ANOVA was used to compare means between groups and showed no significant effect of maternal administration of ethanol, CCL2 or CCR2 antagonist, INCB3344, on these measures
kcal/day kilocalories per day, g grams, INCB3344 CCR2 antagonist