Table 2.

Primary outcome and secondary outcomes in per-protocol population during the follow-up of the study

		PRP group (n = 19)		CS group (n = 17)
	Weeks	Mean ± SD	CI (95%)	Mean ± SD	CI (95%)	p value (intergoup)
A
VAS
V1	0	6.1 ± 1.3	5.4–6.6	6.0 ± 1.5	5.2–6.8	0.9855	ns
V2	1	3.2 ± 2.1	2.2–4.2	2.5 ± 1.7	1.6–3.3	0.3675	ns
V3	5	2.3 ± 1.8	1.4–3.2	2.5 ± 1.5	1.7–3.2	0.6525	ns
V4	15	1.4 ± 1.2	0.8–2.0	3.6 ± 2.1	2.5–4.7	0.001	***
V5	30	1.6 ± 1.9	0.7–2.6	4.0 ± 1.6	3.2–4.8	< 0.0001	****
V6	58	2.9 ± 1.5	2.2–3.6	5.1 ± 1.9	4.1–6.0	0.0008	***
B
IKDC
V1	0	36.3 ± 10.7	31.2–41.4	28.9 ± 8.3	24.6–33.1	0.0570	ns
V2	1	61.2 ± 14.4	54.6–67.4	65.9 ± 13.4	59.0–72.8	0.1925	ns
V3	5	68.8 ± 14.8	61.7–75.9	64.1 ± 17.4	55.2–73.0	0.3747	ns
V4	15	78.7 ± 11.4	73.3–84.2	58.2 ± 15.9	50.1–66.4	0.0004	***
V5	30	77.5 ± 14.2	70.6–84.3	56.3 ± 17.4	47.4–65.3	0.0008	***
V6	58	62.0 ± 15.6	54.5–69.6	39.8 ± 16.3	32.8–46.8	0.0002	***
C
KSS
V1	0	57.8 ± 7.1	54.4–62.2	53.2 ± 8.4	48.8–57.5	0.0998	ns
V2	1	81.3 ± 12.6	75.2–87.4	83.2 ± 9.9	78.1–88.4	0.7598	ns
V3	5	85.7 ± 10.5	80.6–90.7	80.9 ± 11.0	75.3–86.6	0.1925	ns
V4	15	88.8 ± 9.4	84.2–93.3	73.2 ± 13.4	66.2–80.0	0.0013	**
V5	30	86.8 ± 11.9	81.1–92.5	71.2 ± 13.7	64.2–78.3	0.0008	***
V6	58	77.3 ± 12	71.6–83.1	60.3 ± 13.7	53.3–67.3	0.0004	***

Data are provided as mean ± SD (range)

p value of Mann-Whitney test

ns not significant, VAS visual analog scale, KSS Knee Society Score, IKDC International Knee Documentation Committee, CI confidence interval

** Statistically significant difference (p ≤ 0.01)

*** Statistically significant difference (p ≤ 0.001)

**** Statistically significant difference (p ≤ 0.0001)